Antihistamines
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Histamine, released from mast cells when these mast cells are stimulated by the recognition of an allergen or invading pathogen, initiates the response of vasodilation and leaking of neutrophils in the inflammatory response. Antihistamines can help to inhibit this response. There are two histamine receptors - H1 and H2 - that seem to play a role in inflammation:
http://www.nutramed.com/allergy/antihistamines.htm
See also: