Fungi
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Studies suggest that the prostaglandins and thromboxanes produced from Arachidonic Acid during the inflammatory response can help to germinate certain fungi, in particular Candida Albicans and Malassezia yeast. This may be one reason why rosaceans often suffer from seborrheic dermatitis and other fungal infections in addition to their rosacea. Some studies seem to suggest that once established, the fungi also may produce additional pro-inflammatory Arachidonic Acid products (prostaglandins, thromboxanes and leukotrienes) themselves, potentially causing further inflammation.
Useful links:
- Production of Prostaglandins and Leukotrienes by Pathogenic Fungi
- Regulation of Candida albicans morphogenesis by fatty acid metabolites.
- Seborrhoeic dermatitis and Pityrosporum (Malassezia) folliculitis: characterization of inflammatory cells and mediators in the skin by immunohistochemistry
- Seborrheic dermatitis.
