GliSODin

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These pages hold in-progress web pages for the benefit of Rosacea Support Group members. Information provided herein is intended for informational purposes only and is not intended to replace medical advice offered by a physician or qualified healthcare provider. Feedback welcome to wiki-feedback@rosacea-research.org



Cantaloupes contain Superoxide Dismutase

Studies are linking low levels of Superoxide Dismutase, a strong antioxidant (see Antioxidants) with increased inflammation. Studies also show that increasing SOD seems to help alleviate inflammation in such disorders as acne, periodontitis, asthma, and heart disease, amongst other inflammatory diseases:


There are even studies suggesting a link between low levels of SOD and rosacea:


SOD, Glutathione peroxidase and Catalase are the three major enzymes responsible for protecting cells from oxidant stress.

In inflammatory diseases, neutraphils, which are the first line of defense against infectious agents, seem to hang around instead of dying off as they should (through APOPTOSIS), and SOD may be involved in regulating neutrophil apoptosis:

Until now, nobody has been able to create a delivery system for SOD as it is easily broken down by digestion. However, a French company recently combined gliadin (a wheat protein extract) with a 100% vegetarian form of SOD, which comes from cantaloupe melon, in a product called GliSODin and has been able to demonstrate its absorption. They also demonstrated its antioxidant and anti-inflammatory effects on patients during UV exposure, protecting against UV-induced flushing, allergic reaction and pruritus:

It also appears that GliSODin promotes not only SOD, but also Glutathione Peroxidase and Catalase:

As a warning, since GliSODin contains a wheat protein extract, those with wheat allergies should be careful of this supplement.