Role of Excess Blood Vessels

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Small Blood Vessel (magnified view)

The leaking neutrophils associated with the inflammation of rosacea (see Role of Inflammation) are responsible for stimulating Vascular Endothelial Growth Factor (VEGF ) which promotes additional vascular growth, and thus the additional visible and non-visible excess blood vessels associated with rosacea:

Over time, this process builds on itself, more blood vessel growth allows more inflammation, which only creates more blood vessel growth, etc. Something causes the inflammatory response to begin with, but once it starts, the excess blood vessels feed more inflammation, etc.

Potential approaches towards treatment or prevention of progression of rosacea include: