Sleep Influence

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Sleeping Dingo

Many rosaceans have reported that getting adequate amounts of sleep can help with their rosacea symptoms. While there could be many reasons for this, recent research suggests that sleep can shift the balance of Th1 and Th2 cytokine activity and cause a pronounced decrease in production of TNF-alpha:

Sleep associated regulation of T helper 1/T helper 2 cytokine balance in humans.


Sleep deprivation has been associated with a general increase in pro-inflammatory cytokines:

The effects of 40 hours of total sleep deprivation on inflammatory markers in healthy young adults

The relevance of sleep abnormalities to chronic inflammatory conditions

Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation