Staphylococcus genus
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Studies seem to suggest that Staphylococcus aureus may play at least a secondary role in rosacea, particularly in the ocular form. No causative role has been established for S. aureus in rosacea, but studies suggest that people with other skin conditions such as Atopic Dermatitis are often infected with S. aureus and that infection with the pathogen can lead to an upregulated TH2 immune response. Studies also seem to suggest that S. aureus thrives in an abnormal TH2 environment.
Useful links:
- Effects of minocycline on the ocular flora of patients with acne rosacea or seborrheic blepharitis.
- Topical Superantigen Exposure Induces Epidermal Accumulation of CD8+ T Cells, a Mixed Th1/Th2-Type Dermatitis and Vigorous Production of IgE Antibodies in the Murine Model of Atopic Dermatitis.
- Differential susceptibility to staphylococcal superantigen (SsAg)-induced apoptosis of CD4+ T cells from atopic dermatitis patients and healthy subjects: the inhibitory effect of IL-4 on SsAg-induced apoptosis
