Zileuton

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These pages hold in-progress web pages for the benefit of Rosacea Support Group members. Information provided herein is intended for informational purposes only and is not intended to replace medical advice offered by a physician or qualified healthcare provider. Feedback welcome to wiki-feedback@rosacea-research.org



Allergen & Pseudo-Allergen

Zileuton, a prescription 5-LOX inhibitor (see 5-LOX Inhibitors) used to treat asthma, has been shown in one study to reduce the number of inflammatory lesions and decrease sebum production in people with acne:

zileuton reduces sebum production Zileuton, an Oral 5-Lipoxygenase Inhibitor, Directly Reduces Sebum Production

However, another study in acne showed Zileuton had no better effect than placebo:

Zileuton disappoints for acne relief, rosacea hopes dashed also ? Press Release

Still, through its ability to inhibit the production of a host of pro-inflammatory leukotrienes, Zileuton may provide some relief for rosaceans. Only a controlled study of Zileuton specifically for rosacea will tell.